SGLT2 inhibitors reduce heart failure hospitalizations and cardiovascular deaths in diabetic patients

Heart failure and diabetes are closely intertwined.  Diabetes affects not only coronary artery blood flow, but also the myocardium. Patients with type 2 diabetes are at risk of heart failure due to intrinsic myocardial disease, resulting in increased myocardial hypertrophy, fibrosis and stiffness. This can also lead to a form of heart failure described in literature as diabetic cardiomyopathy.

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