Patients experiencing the intractable pain of chronic pancreatitis may be candidates for total pancreatectomy followed by autologous islet cell transplantation (TPIAT). This innovative procedure has been documented to be very effective in controlling pain and restoring insulin secretion in a large number of patients. Baylor University Medical Center, (Baylor Dallas) part of Baylor Scott & White Health, has performed more than 200 successful islet cell transplants, placing it among the top five centers in the United States based on total case volume of this procedure.